Endogenous DNA Damage and Repair Enzymes
نویسندگان
چکیده
منابع مشابه
Endogenous DNA Damage and Repair Enzymes
Tomas Lindahl completed his medical studies at Karolinska Institute in 1970. Yet, his work has always been dedicated to unraveling fundamental mechanisms of DNA decay and DNA repair. His research is characterized with groundbreaking discoveries on the instability of our genome, the identification of novel DNA repair activities, the characterization of DNA repair pathways, and the association to...
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Background: Single nucleotide polymorphisms in 8-oxoguanine DNA glycosylase-1 (OGG1) gene modulates DNA repair capacity and functions as one of the first lines of protective mechanisms against 8-hydroxy-2’-deoxyguanosine (8-OHdG) mutagenicity. OGG1-Cys326 gene polymorphism may decrease DNA repair function, causing oxidative stress due to higher oxidative DNA damage. The main purpose of this stu...
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ژورنال
عنوان ژورنال: Genomics, Proteomics & Bioinformatics
سال: 2016
ISSN: 1672-0229
DOI: 10.1016/j.gpb.2015.11.001